Greenfield Park Elementary was one of several schools built by Greenfield Township prior to its annexation to Detroit in 1917. The school was completed in 1916 and designed by the firm Van Leyen & Schilling. Henry J. Keough served as associate architect on the project.

The school stood east of John R and north of East McNichols, on the southwest corner of Brush and Louisiana streets.

An auditorium, gymnasium, and machine shop were added on a short time later to support the needs of the growing automobile industry. Further additions in 1922 (designed by Malcomson, Higginbotham & Palmer), 1923, and 1927 increased the capacity. As other schools became crowded, the overflow students were sent to Greenfield Park.

Greenfield Park Elementary closed in 2007 due to decreasing population, as the surrounding neighborhood began to become vacant. Between 1998 and 2007, enrollment dropped 56% from 623 to 274. Problems with plumbing and heating contributed to its closure and subsequent abandonment.

The school was demolished in 2016, and its grounds are another vacant lot among many.